Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 4/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23245429 | 0.68 | TRPV4 (0.44) | TRPV4USP14BCAT2BCAT1NOTUM | |
| SCHEMBL7653141 | 0.67 | KDM1A (0.33) | TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL7499656 | 0.67 | BCAT2 (0.41) | TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL20108199 | 0.66 | DHODH (0.44) | — | |
| SCHEMBL29816583 | 0.66 | DHODH (0.44) | — | |
| SCHEMBL6103578 | 0.66 | USP14 (0.38) | TRPV4USP14BCAT2BCAT1NOTUM | |
| SCHEMBL7697079 | 0.64 | USP14 (0.37) | TRPV4USP14BCAT2BCAT1NOTUM | |
| SCHEMBL12413852 | 0.64 | TRPV4 (0.50) | TRPV4PGRAR | |
| SCHEMBL6651303 | 0.64 | TRPV4 (0.71) | TRPV4 | |
| SCHEMBL8193759 | 0.63 | BCAT2 (0.40) | TRPV4USP14BCAT2BCAT1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395683-B1 | CHEMICAL INTERMEDIATE FOR HERBICIDES; APPLYING TO PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-0757673-B1 | HETEROCYCLYLBENZONITRILES | BAYER AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-6100420-A | 2-(SULFONYLAMINO OR DERIVATIVE THEREOF),4-AMINO,5-(HALO OR HYDROGEN)BENZONITRILE OF GIVEN FORMULA; CHEMICAL INTERMEDIATE TO CORRESPONDING 4-HETEROCYCLE BENZONITRILE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-08 | — | — | US | disclosed |
| US-5858925-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0757673-A1 | HETEROCYCLYLBENZONITRILES | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029158-A1 | HETEROCYCLYLBENZONITRILES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-02 | — | — | WO | disclosed |