Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.31 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6103578 | 0.73 | USP14 (0.38) | KDM1AALDH1A1TRPV4USP14BCAT2 | |
| SCHEMBL7697079 | 0.71 | USP14 (0.37) | TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL7740917 | 0.71 | BCAT1 (0.45) | ALDH1A1TRPV4BCAT2BCAT1 | |
| SCHEMBL8193759 | 0.70 | BCAT2 (0.40) | TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL9469169 | 0.69 | BCAT2 (0.34) | USP14BCAT2BCAT1 | |
| SCHEMBL8895927 | 0.68 | TRPV4 (0.39) | KDM1AALDH1A1TRPV4USP14 | |
| SCHEMBL7652708 | 0.67 | TRPV4 (0.38) | TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL8903852 | 0.66 | TRPV4 (0.37) | ALDH1A1TRPV4USP14BCAT2BCAT1 | |
| SCHEMBL9468788 | 0.66 | USP14 (0.33) | USP14BCAT2BCAT1 | |
| SCHEMBL20108199 | 0.65 | DHODH (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495491-B1 | HERBICIDES AND INSECTICIDES; DEFOLIANTS, DESICCANTS, HAULM KILLERS AND ESPECIALLY WEED KILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| EP-0837853-A1 | SUBSTITUTED CYANOPHENYL URACILS | BAYER AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001541-A1 | SUBSTITUTED CYANOPHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |