Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789670 | 0.81 | PTGS2 (0.41) | CA2CA9CA1CA12PTGS2 | |
| SCHEMBL4760307 | 0.76 | CA1 (0.41) | CA2CA9CA1CA12LMNA | |
| SCHEMBL5652598 | 0.68 | CA2 (0.44) | CA2CA9CA1CA12ELANE | |
| SCHEMBL17363903 | 0.68 | KDM4E (0.34) | CA2CA9CA1LMNAMEN1 | |
| SCHEMBL30513622 | 0.67 | CA2 (0.52) | CA2CA9CA1CA12PTGS2 | |
| SCHEMBL7652735 | 0.67 | ELANE (0.37) | CA2CA9CA1CA12RAB9A | |
| Biphenyl SCHEMBL19409340 | 0.66 | CA1 (0.54) | CA2CA9CA1CA12RAB9A | |
| SCHEMBL301797 | 0.66 | CA2 (0.47) | CA2CA9CA1CA12 | |
| SCHEMBL4760304 | 0.66 | CA1 (0.42) | CA2CA9CA1CA12LMNA | |
| Hydrochloric Acid SCHEMBL7362559 | 0.65 | CA2 (0.45) | CA2CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |