Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652506 | 0.94 | TNKS (0.50) | TNKSPARP1TNKS2ADORA3HTT | |
| SCHEMBL7650664 | 0.89 | ADORA3 (0.44) | TNKSPARP1TNKS2ADORA3POLB | |
| SCHEMBL7654423 | 0.84 | ALDH1A1 (0.47) | TNKSTNKS2ADORA3L3MBTL1MAPT | |
| SCHEMBL7652832 | 0.84 | RPA1 (0.51) | ADORA3L3MBTL1HTTGABRA1GABRG2 | |
| SCHEMBL7653825 | 0.84 | ATM (0.58) | TNKSPARP1TNKS2ADORA3L3MBTL1 | |
| SCHEMBL7649183 | 0.80 | CDK4 (0.43) | TNKSPARP1TNKS2ADORA3POLB | |
| SCHEMBL7656228 | 0.79 | ALDH1A1 (0.49) | L3MBTL1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL7660378 | 0.78 | ALDH1A1 (0.53) | TNKSTNKS2L3MBTL1MAPTGAA | |
| SCHEMBL7652867 | 0.78 | ALDH1A1 (0.48) | TNKSPARP1TNKS2POLBL3MBTL1 | |
| SCHEMBL20078779 | 0.78 | TNKS (0.50) | TNKSPARP1TNKS2ADORA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |