Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660378 | 0.94 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRTNKSGUSB | |
| SCHEMBL7650664 | 0.89 | ADORA3 (0.44) | ALDH1A1HPGDTSHRTNKSTNKS2 | |
| SCHEMBL7656709 | 0.85 | NPC1 (0.48) | ALDH1A1HPGDKDM4ELMNAHSD17B10 | |
| SCHEMBL7652937 | 0.84 | TNKS (0.47) | ALDH1A1HPGDTNKSTNKS2KDM4E | |
| SCHEMBL7656767 | 0.84 | GAA (0.54) | ALDH1A1TSHRKDM4EGAACYP1A2 | |
| SCHEMBL7653825 | 0.81 | ATM (0.58) | ALDH1A1HPGDTSHRTNKSGUSB | |
| SCHEMBL7651289 | 0.80 | MAPT (0.44) | ALDH1A1HPGDTNKSGUSBTNKS2 | |
| SCHEMBL7656228 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL7652506 | 0.78 | TNKS (0.50) | ALDH1A1HPGDTNKSTNKS2KDM4E | |
| SCHEMBL7650490 | 0.78 | MAPK11 (0.40) | ALDH1A1TNKSGUSBTNKS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |