Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650664 | 0.90 | ADORA3 (0.44) | ALDH1A1HPGDSRCKDM4EMAPK14 | |
| SCHEMBL5821203 | 0.84 | MAPK14 (0.47) | ALDH1A1GSK3BSRCBRAFKDR | |
| SCHEMBL7649040 | 0.83 | HPGD (0.52) | ALDH1A1HPGDMAPTKDM4ENPY5R | |
| SCHEMBL7660378 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL20078779 | 0.83 | TNKS (0.50) | ALDH1A1HPGDHSD17B10MAPTSRC | |
| SCHEMBL7652506 | 0.83 | TNKS (0.50) | ALDH1A1HPGDHSD17B10MAPTKDM4E | |
| SCHEMBL4549461 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HPGDSRCKDM4EMAPK14 | |
| SCHEMBL7652937 | 0.79 | TNKS (0.47) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7654423 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10MAPTKDM4E | |
| SCHEMBL7659631 | 0.79 | ATM (0.62) | ALDH1A1HPGDKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |