Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653054 | 0.78 | KMT2A (0.43) | KMT2AMEN1SYKALDH1A1TDP1 | |
| SCHEMBL10443906 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL243831 | 0.73 | MEN1 (0.51) | KMT2AMEN1SYKALDH1A1TDP1 | |
| SCHEMBL23094461 | 0.71 | SMN1; SMN2 (0.45) | KMT2AMEN1SYKALDH1A1TDP1 | |
| SCHEMBL8328608 | 0.70 | KMT2A (0.44) | KMT2AALDH1A1POLBMAPTLMNA | |
| SCHEMBL12924638 | 0.70 | LMNA (0.36) | KMT2AMEN1SYKALDH1A1MAPT | |
| SCHEMBL5711752 | 0.69 | TDP1 (0.54) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL8332612 | 0.69 | CCNC (0.49) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL30912635 | 0.69 | ALDH1A1 (0.46) | KMT2AMEN1SYKALDH1A1TDP1 | |
| SCHEMBL1551098 | 0.69 | MEN1 (0.33) | KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482947-B1 | Substituted (hetero) aryl compounds, process for their preparation, agents containing them and their use as safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | claimed |