Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653048 | 0.78 | KMT2A (0.41) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL30912635 | 0.77 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL243831 | 0.76 | MEN1 (0.51) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL16286568 | 0.75 | MMP8 (0.44) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL30441395 | 0.75 | MMP8 (0.44) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL23094461 | 0.73 | SMN1; SMN2 (0.45) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL13900593 | 0.73 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL17389437 | 0.72 | CPB2 (0.49) | KMT2AMEN1ALDH1A1TDP1MAPT | |
| SCHEMBL271585 | 0.72 | MMP8 (0.59) | KMT2AMEN1ALDH1A1TDP1LMNA | |
| SCHEMBL4805423 | 0.71 | OXTR (0.46) | KMT2AMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482947-B1 | Substituted (hetero) aryl compounds, process for their preparation, agents containing them and their use as safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | claimed |