Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CDC7 | O00311 | 5/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328609 | 0.92 | SMN1; SMN2 (0.43) | KMT2ANPSR1ALDH1A1CDC7DBF4 | |
| SCHEMBL5711752 | 0.81 | TDP1 (0.54) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL8332612 | 0.80 | CCNC (0.49) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL7329538 | 0.80 | TAS1R3 (0.51) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL15140360 | 0.79 | PPARG (0.47) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL3512767 | 0.79 | LDHA (0.59) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL5711753 | 0.79 | PPARA (0.53) | KMT2ASMN1; SMN2 | |
| SCHEMBL6712994 | 0.77 | RAB9A (0.48) | KMT2ALMNAMAPTL3MBTL1TP53 | |
| SCHEMBL11662042 | 0.77 | PPARG (0.51) | KMT2ANPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL6034897 | 0.76 | ALDH1A3 (0.53) | KMT2AALDH1A1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |