Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.42 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215644 | 0.82 | AKR1C1 (0.59) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| SCHEMBL17222224 | 0.82 | AKR1C1 (0.59) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| SCHEMBL8112628 | 0.80 | AKR1C1 (0.57) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| SCHEMBL8106538 | 0.80 | AKR1C1 (0.57) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| SCHEMBL8110723 | 0.80 | AKR1C1 (0.57) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| SCHEMBL10550500 | 0.80 | AKR1C1 (0.57) | AKR1C1ALOX15KMT2AOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL8106513 | 0.78 | OPRL1 (0.51) | AKR1C1ALOX15OPRM1OPRL1LMNA | |
| SCHEMBL31016196 | 0.76 | AKR1C1 (0.83) | AKR1C1ALOX15KMT2AHDAC4TET3 | |
| SCHEMBL6391 | 0.76 | AKR1C1 (0.83) | AKR1C1ALOX15KMT2AHDAC4TET3 | |
| SCHEMBL3152584 | 0.76 | AKR1C1 (0.52) | AKR1C1ALOX15KMT2AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358956-B1 | IMIDAZOLYLALKYL-1-PIPERAZINE DERIVATIVES; FARNESYL-PROTEIN AND GERANYLGERANYL TRANSFERASE INHIBITORS; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-03-19 | — | — | US | disclosed |