Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.42 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039206 | 0.85 | ALOX15 (0.44) | AKR1C1OPRM1OPRL1ALOX15CYP2C19 | |
| SCHEMBL10553255 | 0.83 | ALDH1A1 (0.42) | AKR1C1OPRM1OPRL1ALOX15CYP2C19 | |
| SCHEMBL10553259 | 0.83 | ALDH1A1 (0.42) | AKR1C1OPRM1OPRL1ALOX15CYP2C19 | |
| SCHEMBL15215644 | 0.82 | AKR1C1 (0.59) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL17222224 | 0.82 | AKR1C1 (0.59) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL10477046 | 0.81 | AKR1C1 (0.63) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL8106538 | 0.80 | AKR1C1 (0.57) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL8112628 | 0.80 | AKR1C1 (0.57) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL7653247 | 0.80 | AKR1C1 (0.57) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 | |
| SCHEMBL8110723 | 0.80 | AKR1C1 (0.57) | AKR1C1OPRM1OPRL1ALOX15HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857660-A | ENZYME INHIBITORS, ANTICANCER AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |