SCHEMBL765349

SCHEMBL765349

Cc1ccc2c(F)c(C)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
LMNA P02545 2/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
CYP1A2 P05177 7/20 0.52
CYP2A6 P11509 5/20 0.50
TDP1 Q9NUW8 3/20 0.43
SIRT2 Q8IXJ6 1/20 0.39
NCK1 P16333 1/20 0.35
BACE1 P56817 1/20 0.35
KIF11 P52732 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CA12 O43570 3/20 0.34
CA9 Q16790 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18627004 0.86 KDM4E (0.46) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL21507609 0.84 CYP1A2 (0.54) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL15724649 0.83 CYP1A2 (0.43) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL14525486 0.83 CYP1A2 (0.50) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL15724647 0.79 SIRT2 (0.41) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL20065149 0.79 CYP1A2 (0.46) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL17787999 0.79 ALDH1A1 (0.55) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL14525492 0.79 CYP1A2 (0.46) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL607927 0.78 CYP1A2 (0.71) ALDH1A1LMNAHPGDHSD17B10KDM4E
SCHEMBL599166 0.77 ALDH1A1 (0.63) ALDH1A1LMNAHPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME DIC CORPORATION (JP) 2024-07-11 US disclosed
US-20230400721-A1 METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL, METHOD FOR EVALUATING LIQUID CRYSTAL MATERIAL, MEASUREMENT APPARATUS THEREFOR, AND LIQUID CRYSTAL MATERIAL DIC CORPORATION (JP) 2023-12-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
WO-2022234709-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION DEVICE AND ANTENNA EACH USING SAME DIC株式会社 2022-11-10 WO disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-11174431-B2 Liquid crystal composition and liquid crystal display device DIC CORPORATION (JP) 2021-11-16 US disclosed
US-20210139730-A1 DISPERSION AND INKJET INK COMPOSITION, LIGHT CONVERSION LAYER, AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE DISPERSION DIC CORPORATION (JP) 2021-05-13 US disclosed
US-20070187644-A1 Liquid crystal compound, liquid crystal composition, and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2007-08-16 US disclosed
US-7232592-B2 Compounds having a 4,6-difluoroindan-2,5-diyl group; composition of up to 6 compounds gives good response speed, good electrooptical liquid crystal display, matrix liquid crystal display elements DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-19 US disclosed
US-7232592-B2 Compounds having a 4,6-difluoroindan-2,5-diyl group; composition of up to 6 compounds gives good response speed, good electrooptical liquid crystal display, matrix liquid crystal display elements DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-19 US disclosed
EP-1762605-A1 Naphthalene compound with terminal hydrogen, liquid crystal composition including the compound, and LCD device including the liquid crystal composition Chisso Petrochemial Corporation (JP) 2007-03-14 EP disclosed
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION CHISSO PETROCHEMICAL CORPORATION (JP) 2007-03-08 US disclosed
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION CHISSO PETROCHEMICAL CORPORATION (JP) 2007-03-08 US disclosed
US-20070018136-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-01-25 US disclosed
US-20070018136-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-01-25 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION LEF1, CFD, FOXO1 ALDH1A1 2679/4885LMNA 941/4885HPGD 1344/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 ALDH1A1 3448/4885LMNA 3654/4885HPGD 4638/4885
US-20240228878-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AS WELL AS LIQUID CRYSTAL DISPLAY ELEMENT, SENSOR, LIQUID CRYSTAL LENS, OPTICAL COMMUNICATION EQUIPMENT, AND ANTENNA EACH USING THE SAME TTI2, CCT4, CCT2 ALDH1A1 4223/4885LMNA 2416/4885HPGD 4508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.