Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946914 | 0.95 | CFD (0.50) | CFDKDM4EALDH1A1HPGDGLA | |
| SCHEMBL6950743 | 0.83 | AKR1C3 (0.39) | CFDKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7656060 | 0.83 | ADRA1A (0.48) | CFDKDM4EALDH1A1HPGDGLA | |
| SCHEMBL6765694 | 0.82 | ADRA1A (0.50) | CFDKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7653434 | 0.81 | AKR1C3 (0.39) | CFDKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7652743 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1HPGDGLAADRA1A | |
| SCHEMBL6950219 | 0.78 | PDGFRB (0.40) | CFDKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6765436 | 0.78 | ADRA1A (0.47) | CFDADRA1AADRA2CKCNH2ADRA1D | |
| SCHEMBL7010612 | 0.77 | ADRA1A (0.46) | CFDKDM4EALDH1A1HPGDGLA | |
| SCHEMBL6766548 | 0.77 | CFD (0.54) | CFDKDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417194-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | PFIZER, INC. | 2002-07-09 | — | — | US | disclosed |