Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463989 | 0.91 | MMP13 (0.55) | ALDH1A1SMN1; SMN2KDM4EMAPTPPARG | |
| SCHEMBL7625900 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6730256 | 0.89 | MAPT (0.52) | MAPTPPARGEGFRSRCPARG | |
| SCHEMBL6532934 | 0.88 | PPARG (0.56) | ALDH1A1SMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL6234634 | 0.87 | MMP13 (0.58) | ALDH1A1SMN1; SMN2KDM4EMAPTPPARG | |
| SCHEMBL6730033 | 0.86 | PARG (0.52) | ALDH1A1MAPTPPARGEGFRSRC | |
| SCHEMBL7021534 | 0.86 | EGFR (0.50) | EPHX2NR1H4KDM4EMAPTPPARG | |
| SCHEMBL27588010 | 0.85 | PTGER4 (0.51) | ALDH1A1HPGDCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6255321 | 0.85 | MAPT (0.54) | ALDH1A1SMN1; SMN2KDM4EMAPTPPARG | |
| SCHEMBL6736771 | 0.84 | MAPT (0.61) | ALDH1A1HPGDSMN1; SMN2MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | ALDH1A1 1357/4885HPGD 228/4885CYP2C9 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.