SCHEMBL765695

SCHEMBL765695

COc1cc([N+](=O)[O-])ccc1N/N=C(/C(C)=O)C(=O)Nc1ccccc1OCCO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
MAPT P10636 6/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 6/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
PKM P14618 2/20 0.49
HTT P42858 1/20 0.49
EPHX1 P07099 2/20 0.48
KCNMA1 Q12791 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MAPK1 P28482 1/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060616 0.92 MAPT (0.48) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL15314623 0.91 MAPT (0.48) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL13707237 0.91 PKM (0.57) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL12998507 0.87 GAA (0.47) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL12998588 0.86 MAPT (0.55) MAPTKMT2AMEN1ALDH1A1POLB
SCHEMBL765365 0.86 MAPT (0.55) MAPTKMT2AMEN1ALDH1A1POLB
SCHEMBL13115119 0.85 ATM (0.52) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL764920 0.84 MAPT (0.49) MAPTKMT2AMEN1ALDH1A1LMNA
SCHEMBL12299506 0.83 CRHBP (0.53) GAAMAPTKMT2AMEN1ALDH1A1
SCHEMBL15244989 0.82 ALDH1A1 (0.56) GAAMAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7582152-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582151-B2 Pigment dispersion with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20090005474-A1 Pigment Dispersions With Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2009-01-01 US disclosed
US-20080242776-A1 Pigment Dispersion with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-10-02 US disclosed
US-20080227894-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-09-18 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed