Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 10/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070562 | 0.83 | F10 (0.57) | F10F2 | |
| SCHEMBL7076611 | 0.81 | F10 (0.53) | ALDH1A1HTTF10PKMF2 | |
| SCHEMBL7073572 | 0.80 | PKM (0.55) | ALDH1A1HTTMAPTLMNAF10 | |
| SCHEMBL7070020 | 0.80 | MAPT (0.59) | ALDH1A1MAPTLMNAKDM4EADRB2 | |
| SCHEMBL7648189 | 0.80 | LMNA (0.53) | HTTMAPTLMNAKDM4EF10 | |
| SCHEMBL7076926 | 0.79 | LSS (0.52) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL7655612 | 0.76 | MAOA (0.42) | HTTMAPTLMNAHPGDTHRB | |
| SCHEMBL7649437 | 0.76 | PKM (0.46) | ALDH1A1MAPTLMNAF10PKM | |
| SCHEMBL7070051 | 0.76 | LMNA (0.52) | ALDH1A1HTTMAPTLMNAHPGD | |
| SCHEMBL7071746 | 0.75 | MEN1 (0.54) | ALDH1A1HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |