Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653811 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL7662323 | 0.84 | TRPM8 (0.39) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7662318 | 0.84 | TRPM8 (0.39) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7663718 | 0.84 | HCRTR1 (0.35) | L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL7663712 | 0.84 | HCRTR1 (0.35) | L3MBTL1NPC1ALDH1A1 | |
| SCHEMBL7169217 | 0.81 | HPGD (0.36) | LMNAALDH1A1 | |
| SCHEMBL7169218 | 0.81 | HPGD (0.36) | LMNAALDH1A1 | |
| SCHEMBL10387139 | 0.81 | PPARG (0.47) | KMT2AL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL10387140 | 0.81 | PPARG (0.47) | KMT2AL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL7662857 | 0.80 | ALDH1A1 (0.41) | L3MBTL1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465457-B1 | CONTROLLING PATHOGENS ON PLANTS OR SEEDS | ZENECA LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |
| US-5585513-A | CHEMICAL INTERMEDIATES | ZENECA LIMITED (GB) | 1996-12-17 | — | — | US | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |