Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815262 | 0.85 | CYP3A4 (0.49) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7948375 | 0.84 | MAPK1 (0.49) | AVPR2OXTRAVPR1AFADS1LMNA | |
| SCHEMBL6814742 | 0.79 | KDM4E (0.54) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7908169 | 0.78 | ALDH1A1 (0.45) | LMNANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6819363 | 0.78 | KMT2A (0.56) | LMNATP53NPC1RAB9AMAPT | |
| SCHEMBL6814866 | 0.77 | KMT2A (0.52) | LMNATP53NPC1RAB9AMAPT | |
| SCHEMBL7654038 | 0.77 | MAPT (0.41) | AVPR2OXTRAVPR1AFADS1LMNA | |
| SCHEMBL6815804 | 0.75 | NPC1 (0.49) | LMNATP53NPC1RAB9AMAPT | |
| SCHEMBL6814354 | 0.74 | SMN1; SMN2 (0.47) | LMNATP53NPC1RAB9AMAPT | |
| SCHEMBL6819261 | 0.74 | KCNMA1 (0.53) | FADS1LMNATP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |