Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 9/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654104 | 1.00 | TPSAB1 (0.56) | TPSAB1PLGPRSS1BACE1EPHX2 | |
| SCHEMBL15382444 | 0.87 | TPSAB1 (0.53) | TPSAB1PLGPRSS1BACE1POLB | |
| SCHEMBL30279569 | 0.86 | BACE1 (0.59) | TPSAB1PLGPRSS1BACE1KMT2A | |
| SCHEMBL2393583 | 0.86 | BACE1 (0.59) | TPSAB1PLGPRSS1BACE1KMT2A | |
| SCHEMBL29253632 | 0.86 | BACE1 (0.59) | TPSAB1PLGPRSS1BACE1KMT2A | |
| SCHEMBL13316870 | 0.85 | CTSS (0.55) | BACE1CA2CA1PPID | |
| SCHEMBL1752677 | 0.85 | CTSK (0.60) | TPSAB1PLGPRSS1BACE1KMT2A | |
| SCHEMBL24347009 | 0.84 | BACE1 (0.60) | BACE1KMT2A | |
| SCHEMBL23461953 | 0.84 | TPSAB1 (0.50) | TPSAB1PLGPRSS1BACE1POLB | |
| SCHEMBL23832942 | 0.84 | CA2 (0.50) | TPSAB1PLGPRSS1BACE1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |