Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649027 | 0.86 | ADRA1D (0.44) | EHMT2EHMT1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7652743 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL6950743 | 0.85 | AKR1C3 (0.39) | EHMT2EHMT1KDM4EALDH1A1HPGD | |
| SCHEMBL6951033 | 0.84 | AKR1C3 (0.41) | KDM4EALDH1A1HPGDGLAHSD17B10 | |
| SCHEMBL7653434 | 0.83 | AKR1C3 (0.39) | EHMT2EHMT1TLR9TLR7KDM4E | |
| SCHEMBL7653453 | 0.82 | TLR9 (0.49) | EHMT2TLR9TLR7KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7652032 | 0.81 | TLR9 (0.49) | EHMT2TLR9TLR7KDM4EHPGD | |
| SCHEMBL7006705 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL7011047 | 0.79 | KDM4E (0.47) | EHMT2EHMT1KDM4EALDH1A1HPGD | |
| SCHEMBL6767113 | 0.77 | AKR1C3 (0.41) | KDM4EALDH1A1HPGDHSD17B10ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417194-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | PFIZER, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6048864-A | Quinolines and quinazolines useful in therapy | PFIZER INC (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0887344-A1 | Quinolines and quinazolines useful in therapy | Pfizer Limited (GB) | 1998-12-30 | — | — | EP | disclosed |