Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011047 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL7649027 | 0.88 | ADRA1D (0.44) | AKR1C3 | |
| SCHEMBL7013220 | 0.86 | ADRA1A (0.56) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL7653453 | 0.85 | TLR9 (0.49) | KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7652032 | 0.85 | TLR9 (0.49) | KDM4EHPGD | |
| SCHEMBL6765566 | 0.83 | AKR1C3 (0.45) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL6767075 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL7654368 | 0.81 | EHMT2 (0.47) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL7014073 | 0.79 | ADRA1A (0.56) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL7011919 | 0.79 | ADRA2B (0.53) | KDM4EALDH1A1HSD17B10TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875506-B1 | Quinoline and quinazoline compounds useful in therapy | PFIZER LTD (GB) | 2003-02-26 | — | — | EP | disclosed |