Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660381 | 0.94 | KMT2A (0.54) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7650665 | 0.89 | KDM4E (0.64) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7656717 | 0.85 | MEN1 (0.53) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7652940 | 0.84 | KDM4E (0.51) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7656771 | 0.84 | RAD51 (0.46) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7653827 | 0.81 | KDM4E (0.48) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7651292 | 0.80 | GABRA1 (0.43) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7656234 | 0.79 | ALDH1A1 (0.53) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7652511 | 0.78 | KDM4E (0.51) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7650494 | 0.78 | KDM4E (0.45) | KDM4EKMT2AMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |