Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659636 | 0.94 | MEN1 (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7656036 | 0.86 | ALKBH5 (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7650665 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7652940 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7654427 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7652511 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7657337 | 0.77 | MGLL (0.46) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7656234 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7660381 | 0.75 | KMT2A (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7652917 | 0.74 | GAA (0.52) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |