SCHEMBL7654545

SCHEMBL7654545

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1C=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.41
HNF4A P41235 1/20 0.41
PTPN6 P29350 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PIM1 P11309 1/20 0.38
LMNA P02545 1/20 0.38
SMO Q99835 1/20 0.37
TSHR P16473 1/20 0.37
GLA P06280 1/20 0.37
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7656900 0.87 HSD17B10 (0.43) KDM4EMEN1ALDH1A1POLBKMT2A
SCHEMBL7077665 0.80 LMNA (0.42) ALDH1A1LMNATSHRCYP2C19CYP1A2
SCHEMBL4036668 0.77 LMNA (0.40) MEN1ALDH1A1KMT2ALMNATSHR
SCHEMBL4271639 0.77 LMNA (0.40) MEN1ALDH1A1KMT2ALMNATSHR
SCHEMBL7807426 0.76 LMNA (0.47) MEN1ALDH1A1KMT2ALMNATSHR
SCHEMBL31544300 0.75 TSHR (0.55) KDM4EALDH1A1HSD17B10LMNATSHR
SCHEMBL7948238 0.75 LMNA (0.44) ALDH1A1LMNATSHRCYP2C19CYP1A2
SCHEMBL7573192 0.73 LMNA (0.45) KDM4EMEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9640727 0.73 LMNA (0.45) KDM4EALDH1A1HSD17B10LMNATSHR
SCHEMBL4032987 0.73 LMNA (0.45) MEN1ALDH1A1KMT2AHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372693-B1 AGRICULTURAL HERBICIDES FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
US-6143696-A FOR CROP PROTECTION; HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed