SCHEMBL7948238

SCHEMBL7948238

CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.43
FABP4 P15090 5/20 0.43
FABP3 P05413 3/20 0.43
FABP5 Q01469 2/20 0.43
ALDH1A1 P00352 1/20 0.42
ACLY P53396 7/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP13 P45452 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7951354 0.89 LMNA (0.43) LMNATSHRALDH1A1ACLY
SCHEMBL7946301 0.85 ACLY (0.44) LMNAALDH1A1ACLYCA1CA2
SCHEMBL7946291 0.84 SMN1; SMN2 (0.44) LMNAFABP4FABP3ALDH1A1ACLY
SCHEMBL7807426 0.80 LMNA (0.47) LMNATSHRALDH1A1CA1CA2
SCHEMBL31544300 0.78 TSHR (0.55) LMNATSHRALDH1A1ACLYCA1
SCHEMBL7946304 0.78 L3MBTL1 (0.40) LMNAACLY
SCHEMBL9640727 0.77 LMNA (0.45) LMNATSHRALDH1A1CA1CA2
SCHEMBL4032987 0.77 LMNA (0.45) LMNATSHRALDH1A1ACLYCYP1A2
SCHEMBL27967782 0.77 FABP4 (0.50) TSHRFABP4FABP3FABP5ALDH1A1
SCHEMBL7573192 0.77 LMNA (0.45) LMNATSHRALDH1A1ACLYAKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed
EP-0914317-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 1999-05-12 EP disclosed
WO-1998052926-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-11-26 WO disclosed