SCHEMBL7656900

SCHEMBL7656900

COC(=O)c1ccc(S(C)(=O)=O)c(C=Cc2ccccc2)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
POLB P06746 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
KDM4E B2RXH2 5/20 0.38
MAPT P10636 4/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP3A4 P08684 2/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7654545 0.87 PTPN1 (0.41) HSD17B10CYP1A2CYP2C19POLBCA1
SCHEMBL4267428 0.81 VCAM1 (0.40) HSD17B10NPC1RAB9ACA1CA2
SCHEMBL5835866 0.80 ALDH1A1 (0.42) HSD17B10CYP1A2CYP2C19NPC1RAB9A
SCHEMBL7946301 0.77 ACLY (0.44) HSD17B10RAB9ACA1CA2CA5A
SCHEMBL4276213 0.77 VCAM1 (0.37) HSD17B10NPC1RAB9ACA1CA2
SCHEMBL4267417 0.77 VCAM1 (0.37) HSD17B10NPC1RAB9ACA1CA2
SCHEMBL4278676 0.75 VCAM1 (0.40) HSD17B10CYP1A2CYP2C19CA1CA2
SCHEMBL4268094 0.75 KDM4E (0.44) HSD17B10NPC1RAB9ACA1CA2
SCHEMBL7627991 0.75 MITF (0.43) HSD17B10CA1CA2CA5ACA9
SCHEMBL30230387 0.74 CA1 (0.41) HSD17B10POLBCA1CA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372693-B1 AGRICULTURAL HERBICIDES FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2002-04-16 US disclosed
US-6143696-A FOR CROP PROTECTION; HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed