Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655707 | 0.85 | P4HTM (0.37) | MEN1KMT2ACYP2C19 | |
| SCHEMBL7663607 | 0.83 | — | — | |
| SCHEMBL7655191 | 0.82 | CNR2 (0.30) | — | |
| SCHEMBL7663615 | 0.80 | SIRT6 (0.30) | — | |
| SCHEMBL7661229 | 0.80 | CYP1A2 (0.38) | — | |
| SCHEMBL7651976 | 0.77 | KMT2A (0.37) | MEN1KMT2ACYP2C19 | |
| SCHEMBL7103531 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7104707 | 0.75 | PNP (0.36) | MEN1KMT2A | |
| SCHEMBL7108522 | 0.71 | SMO (0.40) | MEN1KMT2A | |
| SCHEMBL7106490 | 0.69 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |