Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218881 | 0.88 | CYP2A6 (0.58) | TSHRCYP2A6MAPTCYP1A2NCEH1 | |
| SCHEMBL25969601 | 0.82 | MAPT (0.61) | TSHRCYP2A6MAPTCYP1A2LMNA | |
| SCHEMBL10006897 | 0.81 | LTA4H (0.55) | TSHRCYP1A2LMNAHTTHSD17B10 | |
| SCHEMBL11566452 | 0.80 | PPARG (0.59) | CYP1A2NCEH1KDM4EKMT2AHPGD | |
| SCHEMBL11579591 | 0.79 | NCEH1 (0.49) | TSHRCYP2A6MAPTCYP1A2NCEH1 | |
| SCHEMBL1052575 | 0.78 | MAPT (0.52) | TSHRCYP2A6MAPTCYP1A2HSD17B10 | |
| SCHEMBL25205 | 0.78 | MAPT (0.67) | TSHRCYP2A6MAPTCYP1A2NCEH1 | |
| SCHEMBL2242408 | 0.77 | MAPT (0.46) | TSHRCYP2A6MAPTLMNAHSD17B10 | |
| SCHEMBL7654717 | 0.77 | MAPT (0.46) | TSHRCYP2A6MAPTCYP1A2LMNA | |
| SCHEMBL10978313 | 0.77 | NCEH1 (0.50) | TSHRCYP2A6MAPTCYP1A2NCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108683-A1 | COVALENT RAS INHIBITORS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-20150368213-A1 | Novel Inhibitors of System Xc- | THE UNIVERSITY OF MONTANA | 2015-12-24 | — | — | US | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368213-A1 | Novel Inhibitors of System Xc- | SLC7A11, SLC1A1, SLC1A2 | TSHR 1576/4885CYP2A6 2721/4885MAPT 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.