Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8578214 | 0.89 | NCEH1 (0.58) | MAPTTSHRCYP2A6CYP1A2NCEH1 | |
| SCHEMBL218881 | 0.84 | CYP2A6 (0.58) | MAPTTSHRCYP2A6CYP1A2NCEH1 | |
| SCHEMBL13021645 | 0.82 | NQO1 (0.64) | MAPTCYP2A6CYP1A2NQO1HPGD | |
| SCHEMBL24299849 | 0.81 | NCEH1 (0.57) | MAPTTSHRCYP2A6CYP1A2NCEH1 | |
| SCHEMBL998182 | 0.80 | MAPT (1.00) | MAPTTSHRCYP2A6CYP1A2NQO1 | |
| SCHEMBL29428410 | 0.80 | MAPT (1.00) | MAPTTSHRCYP2A6CYP1A2NQO1 | |
| SCHEMBL19766698 | 0.79 | MAPT (0.62) | MAPTCYP1A2NQO1KMT2AMEN1 | |
| SCHEMBL8731312 | 0.79 | NCEH1 (0.47) | MAPTTSHRCYP2A6CYP1A2NCEH1 | |
| SCHEMBL278576 | 0.78 | MAPT (0.67) | MAPTTSHRCYP2A6CYP1A2NQO1 | |
| SCHEMBL30380487 | 0.78 | MAPT (0.67) | MAPTTSHRCYP2A6CYP1A2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014764-A1 | N-myristoyltransferase inhibitor compositions and methods of use | SMITH CHARLES D (US) | 2004-01-22 | — | — | US | claimed |
| US-20230303586-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303586-A1 | INHIBITORS OF KRAS G12C | ARAXES PHARMA LLC (US) | 2023-09-28 | — | — | US | disclosed |
| WO-2023150374-A1 | INDUCERS OF KLF2 AND METHODS OF USE THEREOF | RIPARIAN PHARMACEUTICALS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-4169902-A1 | SPERMINE DERIVATIVES AS HEPARIN ANTIDOTES | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2023-04-26 | — | — | EP | disclosed |
| US-11566016-B2 | MAP kinase modulators and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-31 | — | — | US | disclosed |
| US-20230015617-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2023-01-19 | — | — | US | disclosed |
| US-20220216422-A1 | Electroluminescent Device | UDC IRELAND LTD (IE) | 2022-07-07 | — | — | US | disclosed |
| US-11339182-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220135605-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-05-05 | — | — | US | disclosed |
| WO-1999011655-A1 | MODULAR PROTEIN LIBRARIES AND METHODS OF PREPARATION | GRYPHON SCIENCES (US) | 1999-03-11 | — | — | WO | disclosed |
| US-5840684-A | Glycopeptide antibiotic derivatives | ELI LILLY AND COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| CN-1183773-A | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | UPJOHN CO (US) | 1998-06-03 | — | — | CN | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5324324-A | Coated implantable stimulation electrode and lead | SIEMENS PACESETTER, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |
| CN-1046528-A | As the new naphthalane base-3H-1 of antihyperglycemic agents, 2,3,5-oxygen thia diazole 2-oxide compound | AMERICAN HOME PROD (US) | 1990-10-31 | — | — | CN | disclosed |
| US-4276305-A | INSECTICIDES, MITICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566016-B2 | MAP kinase modulators and uses thereof | MAPK1, MAP3K1, MAP3K2 | MAPT 30/4885TSHR 4665/4885CYP2A6 4660/4885 |
| US-20220135605-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, TRPA1 | MAPT 601/4885TSHR 1622/4885CYP2A6 3406/4885 |
| US-20230015617-A1 | PHTHALAZINONE DERIVATIVES | NR0B1, NR0B2, NR2E1 | MAPT 4216/4885TSHR 187/4885CYP2A6 950/4885 |
| US-20220216422-A1 | Electroluminescent Device | PNPO, ODC1, AXL | MAPT 459/4885TSHR 2334/4885CYP2A6 3311/4885 |
| US-20040014764-A1 | N-myristoyltransferase inhibitor compositions and methods of use | NMT2, NMT1, MBOAT1 | MAPT 133/4885TSHR 4586/4885CYP2A6 3929/4885 |
| US-11339182-B2 | Organic electroluminescent materials and devices | CRY2, CRY1, CRYAA | MAPT 2505/4885TSHR 2355/4885CYP2A6 930/4885 |
| US-20230303586-A1 | INHIBITORS OF KRAS G12C | KRAS, NRAS, HRAS | MAPT 279/4885TSHR 1662/4885CYP2A6 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.