Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.66 |
| ▸ | ITGAV | P06756 | 13/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.66 |
| ▸ | HPGDS | O60760 | 2/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383582 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BHPGDSADRB3 | |
| SCHEMBL382763 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVITGA2BHPGDSSFRP1 | |
| SCHEMBL7662919 | 0.83 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL382705 | 0.82 | ITGB3 (0.95) | ITGB3ITGAVITGA2B | |
| SCHEMBL382702 | 0.80 | ITGB3 (0.46) | ITGB3ITGAVITGA2BHPGDSCASR | |
| SCHEMBL382545 | 0.80 | ITGB3 (0.46) | ITGB3ITGAVITGA2BHPGDSCASR | |
| SCHEMBL7656383 | 0.80 | ITGB3 (0.44) | ITGB3ITGAVITGA2BHPGDSSFRP1 | |
| SCHEMBL383585 | 0.79 | ITGB3 (0.64) | ITGB3ITGAVITGA2BHPGDSSFRP1 | |
| SCHEMBL382772 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7655428 | 0.79 | HPGDS (0.44) | ITGB3ITGAVITGA2BHPGDSSFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |