Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656663 | 0.77 | HDAC1 (0.46) | ALDH1A1MEN1KMT2AMAPTHDAC1 | |
| SCHEMBL7654886 | 0.76 | HDAC1 (0.48) | PTGS2MAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL7648500 | 0.75 | HDAC1 (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7648551 | 0.74 | HDAC1 (0.51) | LMNAALDH1A1MAPTHDAC1HDAC8 | |
| SCHEMBL7648583 | 0.74 | HDAC1 (0.59) | ALDH1A1MEN1KMT2AMAPTHDAC1 | |
| SCHEMBL7654277 | 0.73 | CCR2 (0.45) | PTGS2LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7650053 | 0.72 | HDAC1 (0.52) | LMNAALDH1A1MAPTKDM4EHDAC1 | |
| SCHEMBL7648333 | 0.71 | HDAC6 (0.48) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7656537 | 0.71 | HDAC1 (0.47) | TSHRALDH1A1MAPTHDAC1HDAC8 | |
| SCHEMBL7651811 | 0.70 | TDP1 (0.47) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |