Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 3/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651794 | 0.78 | CYP19A1 (0.45) | BCHEMAOBSNCACYP1B1MAPK1 | |
| SCHEMBL7651789 | 0.73 | SNCA (0.44) | BCHEMAOBSNCACYP1B1POLB | |
| SCHEMBL8976663 | 0.72 | L3MBTL1 (0.47) | MAOBMAPK1POLBCES2CES1 | |
| SCHEMBL1405432 | 0.69 | CYP19A1 (0.72) | BCHEMAOBSNCACYP1B1MAPK1 | |
| SCHEMBL1405433 | 0.69 | CYP19A1 (0.72) | BCHEMAOBSNCACYP1B1MAPK1 | |
| SCHEMBL29136503 | 0.69 | CYP19A1 (0.72) | BCHEMAOBSNCACYP1B1MAPK1 | |
| Benzophenone SCHEMBL27490408 | 0.69 | POLB (0.79) | BCHEMAOBMAPK1POLBCES2 | |
| SCHEMBL229627 | 0.68 | POLB (0.82) | MAPK1POLBCES2CES1MAPT | |
| Benzophenone SCHEMBL28231509 | 0.68 | POLB (0.82) | MAPK1POLBCES2CES1MAPT | |
| SCHEMBL11803175 | 0.68 | MAOB (1.00) | BCHEMAOBCYP1B1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |