Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 6/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650218 | 0.89 | MGLL (0.43) | HSD17B1HSD17B2MMP2MGLLCA2 | |
| SCHEMBL19692836 | 0.89 | MGLL (0.43) | HSD17B1HSD17B2MMP2MGLLCA2 | |
| SCHEMBL55285 | 0.86 | CA1 (0.44) | CA2CA12CA9ALDH1A1CYP3A4 | |
| SCHEMBL9162922 | 0.83 | CA2 (0.48) | HSD17B1HSD17B2MMP2MGLLCA2 | |
| SCHEMBL11331630 | 0.81 | HSD17B1 (0.47) | HSD17B1HSD17B2MMP2MGLLCA2 | |
| SCHEMBL31385343 | 0.79 | HSD17B1 (0.45) | HSD17B1HSD17B2MGLLCA2CA12 | |
| SCHEMBL7220092 | 0.79 | MGLL (0.43) | HSD17B1HSD17B2MMP2MGLLCA2 | |
| SCHEMBL29650282 | 0.79 | PSIP1 (0.56) | HSD17B1HSD17B2MMP2CA2CA12 | |
| SCHEMBL2642996 | 0.79 | PSIP1 (0.56) | HSD17B1HSD17B2MMP2CA2CA12 | |
| SCHEMBL4392802 | 0.78 | LMNA (0.57) | CA2CA12CA9ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-6486354-B1 | Solid phase supports | AKZO NOBEL N.V. (NL) | 2002-11-26 | — | — | US | disclosed |