Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | PGC | P20142 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656163 | 0.91 | CCR1 (0.44) | ACE2CMA1 | |
| SCHEMBL7660638 | 0.89 | CCR1 (0.46) | ACE2CMA1CTSD | |
| SCHEMBL7668192 | 0.89 | CAPN1 (0.49) | CMA1CTSD | |
| SCHEMBL7665779 | 0.89 | PREP (0.38) | ACE2CMA1CTSD | |
| SCHEMBL7664392 | 0.89 | ELANE (0.47) | CMA1 | |
| SCHEMBL7662792 | 0.89 | CA2 (0.40) | ACE2CMA1 | |
| SCHEMBL7659218 | 0.88 | CMA1 (0.52) | CMA1 | |
| SCHEMBL7655849 | 0.87 | CTSD (0.46) | CTSD | |
| Hydrochloric Acid SCHEMBL7665936 | 0.86 | HSD17B10 (0.40) | ACE2CMA1 | |
| SCHEMBL5711224 | 0.84 | CMA1 (0.48) | ACE2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |