Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 5/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655849 | 0.92 | CTSD (0.46) | PSMB5CTSD | |
| SCHEMBL7661652 | 0.91 | PREP (0.39) | PREPPSMB5CTSDACE | |
| SCHEMBL7656163 | 0.91 | CCR1 (0.44) | CMA1ACEACE2 | |
| SCHEMBL7660638 | 0.89 | CCR1 (0.46) | CMA1CTSDACEACE2 | |
| SCHEMBL7655898 | 0.89 | ACE2 (0.46) | CMA1CTSDACE2 | |
| SCHEMBL7664392 | 0.86 | ELANE (0.47) | CMA1 | |
| SCHEMBL7668192 | 0.86 | CAPN1 (0.49) | PREPCMA1CTSD | |
| SCHEMBL7659218 | 0.86 | CMA1 (0.52) | CMA1KLK5 | |
| SCHEMBL5711388 | 0.85 | CMA1 (0.43) | CMA1PSMB5 | |
| SCHEMBL7662792 | 0.85 | CA2 (0.40) | CMA1ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |