Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657259 | 0.91 | NPC1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL6952449 | 0.89 | MMP2 (0.45) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL7650918 | 0.88 | NPC1 (0.40) | KDM4ENPC1RAB9AMMP2LMNA | |
| SCHEMBL6945281 | 0.88 | MAPT (0.47) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL7649497 | 0.87 | NPC1 (0.41) | HPGDNPC1RAB9AMMP2HDAC6 | |
| SCHEMBL7653164 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL529011 | 0.86 | RAB9A (0.48) | ALDH1A1NPC1RAB9AMMP2HDAC6 | |
| SCHEMBL7654851 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL7656006 | 0.83 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL6953839 | 0.80 | POLB (0.42) | ALDH1A1HSD17B10NPC1RAB9AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |