Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656015 | 0.91 | ALDH1A1 (0.42) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL6945281 | 0.87 | MAPT (0.47) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL6952449 | 0.87 | MMP2 (0.45) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL7653164 | 0.85 | ALDH1A1 (0.42) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL7650918 | 0.85 | NPC1 (0.40) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL7657249 | 0.84 | NPC1 (0.39) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL7649497 | 0.84 | NPC1 (0.41) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL7654851 | 0.83 | ALDH1A1 (0.50) | NPC1RAB9AMMP2MAPTKDM4E | |
| SCHEMBL529011 | 0.83 | RAB9A (0.48) | NPC1RAB9AMMP2MAPTHDAC6 | |
| SCHEMBL6953839 | 0.79 | POLB (0.42) | NPC1RAB9AMMP2MAPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |