Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653827 | 0.86 | KDM4E (0.48) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7659636 | 0.86 | MEN1 (0.51) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7652834 | 0.83 | ALKBH5 (0.48) | ALKBH5KMT2AMEN1RAB9AMAPT | |
| SCHEMBL7650665 | 0.82 | KDM4E (0.64) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7656717 | 0.82 | MEN1 (0.53) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7655381 | 0.81 | KDM4E (0.48) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7652940 | 0.76 | KDM4E (0.51) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7652511 | 0.76 | KDM4E (0.51) | KMT2AMEN1RAB9AMAPTGAA | |
| SCHEMBL7657337 | 0.75 | MGLL (0.46) | KMT2AMEN1MAPTGAACYP1A2 | |
| SCHEMBL7656771 | 0.75 | RAD51 (0.46) | ALKBH5KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |