Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660819 | 0.88 | KDM4E (0.53) | ALDH1A1KDM4EHPGDATMMAPT | |
| SCHEMBL7658336 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDATMMAPT | |
| SCHEMBL8072656 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EHPGDATMMAPT | |
| SCHEMBL7655361 | 0.81 | KDM4E (0.48) | ALDH1A1KDM4EHPGDATMMAPT | |
| SCHEMBL8250528 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL7651195 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL8250523 | 0.77 | HSD17B10 (0.50) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL7662862 | 0.76 | ALOX5 (0.40) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL7655721 | 0.75 | ALOX5 (0.49) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL2954102 | 0.75 | KMT2A (0.48) | ALDH1A1KDM4EHPGDATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |