Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660819 | 0.88 | KDM4E (0.53) | ALDH1A1KDM4EHPGDPKMALOX5 | |
| SCHEMBL7656174 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDPKMALOX5 | |
| SCHEMBL7662862 | 0.86 | ALOX5 (0.40) | ALDH1A1KDM4EHPGDPKMALOX5 | |
| SCHEMBL7650694 | 0.84 | KDM4E (0.37) | ALDH1A1KDM4EHPGDPKMADORA3 | |
| SCHEMBL7662426 | 0.80 | ADORA3 (0.43) | ALDH1A1KDM4EHPGDADORA3ADORA1 | |
| SCHEMBL7650682 | 0.76 | POLB (0.36) | ALDH1A1KDM4EHPGDPKMADORA3 | |
| SCHEMBL7655721 | 0.75 | ALOX5 (0.49) | ALDH1A1KDM4EHPGDPKMALOX5 | |
| SCHEMBL8250528 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EHPGDPKMLMNA | |
| SCHEMBL7651195 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EHPGDPKMLMNA | |
| SCHEMBL2954675 | 0.73 | FABP3 (0.40) | ALDH1A1KDM4EHPGDPKMADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |