SCHEMBL7656175

SCHEMBL7656175

CCCc1cccc(Oc2ccccc2)c1Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.50
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 2/20 0.49
RIPK1 Q13546 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
BCL2L2 Q92843 1/20 0.41
LTA4H P09960 2/20 0.41
DPP4 P27487 1/20 0.40
AR P10275 1/20 0.40
SLC6A3 Q01959 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347268 0.87 PPARA (0.49) HRH1SLC6A2SLC6A4RIPK1L3MBTL1
SCHEMBL1696335 0.85 HRH1 (0.67) HRH1SLC6A2SLC6A4RIPK1BCL2L2
SCHEMBL29815703 0.85 HRH1 (0.67) HRH1SLC6A2SLC6A4RIPK1BCL2L2
SCHEMBL29406841 0.85 HRH1 (0.42) HRH1SLC6A2SLC6A4RIPK1POLB
SCHEMBL983636 0.81 IAPP (0.41) POLBLTA4HNPSR1
SCHEMBL3930496 0.81 HRH1 (0.53) HRH1SLC6A2SLC6A4RIPK1BCL2L2
SCHEMBL19808529 0.81 LTA4H (0.40) HRH1SLC6A2SLC6A4RIPK1BCL2L2
SCHEMBL2763252 0.81 HRH1 (0.41) HRH1SLC6A2SLC6A4RIPK1LTA4H
SCHEMBL11352187 0.79 HRH1 (0.49) HRH1SLC6A2SLC6A4RIPK1L3MBTL1
SCHEMBL7784167 0.78 LTB4R (0.50) HRH1SLC6A2SLC6A4RIPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420593-A2 Terminal-modified imide oligomer composition UBE INDUSTRIES, LTD. (JP) 1991-04-03 EP claimed
US-4931541-A ETHYNYLATION OF HALOGENATED BENZOXAZINONE FOLLOWED BY CONDENSATION WITH AROMATIC PRIMARY DIAMINE AND BULK POLY; HEAT RESISTANCE; ADHESIVES, ELECTRONICS CENTRE D'ETUDE DES MATERIAUX ORGANIQUES POUR TECHNOLOGIES AVANCEES (FR) 1990-06-05 US claimed
US-6492030-B1 SILOXANE DENATURED POLYIMIDE, DI- OR TRIALLYL COMPOUND AND DIMALEIMIDE COMPOUND; ADHERES TO METALS WITH LOW DIELECTRIC CONSTANT AND DISSIPATION FACTOR; FASTER SIGNAL PROCESSING; HIGH FREQUENCY ELECTRONICS WITH MINIATURIZED CIRCUITS TOMOEGAWA PAPER CO., LTD. (JP) 2002-12-10 US disclosed