Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652917 | 0.81 | GAA (0.52) | MAPTCXCR2NPC1RAB9AMEN1 | |
| SCHEMBL7650665 | 0.78 | KDM4E (0.64) | TP53MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7652511 | 0.78 | KDM4E (0.51) | TP53MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7658239 | 0.76 | ALDH1A1 (0.62) | TP53MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7652940 | 0.75 | KDM4E (0.51) | TP53MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7656234 | 0.73 | ALDH1A1 (0.53) | TP53MAPTCXCR2NPC1RAB9A | |
| SCHEMBL7649045 | 0.73 | HPGD (0.49) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL7660381 | 0.72 | KMT2A (0.54) | MAPTCXCR2NPC1RAB9AMEN1 | |
| SCHEMBL7652870 | 0.72 | KDM4E (0.44) | TP53MAPTNPC1RAB9AMEN1 | |
| SCHEMBL7659636 | 0.72 | MEN1 (0.51) | TP53MAPTCXCR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |