Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146047 | 0.77 | KDM4E (0.47) | ALDH1A1HSD17B10LMNAKDM4ENPC1 | |
| SCHEMBL7652511 | 0.76 | KDM4E (0.51) | ALDH1A1HSD17B10LMNAKDM4ENPC1 | |
| SCHEMBL7656287 | 0.76 | TP53 (0.49) | ALDH1A1HSD17B10LMNAKDM4ENPC1 | |
| SCHEMBL7650665 | 0.76 | KDM4E (0.64) | ALDH1A1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL11177031 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNAKDM4ENPC1 | |
| SCHEMBL29143074 | 0.75 | NOX4 (0.45) | ALDH1A1HSD17B10MAPTHPGDMEN1 | |
| SCHEMBL28364722 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14446895 | 0.73 | KDM4E (0.66) | ALDH1A1HSD17B10LMNAKDM4ENPC1 | |
| SCHEMBL7652940 | 0.73 | KDM4E (0.51) | ALDH1A1LMNAKDM4ENPC1RAB9A | |
| SCHEMBL17629066 | 0.72 | TSHR (0.45) | ALDH1A1HSD17B10LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819358-B | Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt | 湖南化工研究院有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-115819358-A | Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt | 湖南化工研究院有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-112225705-A | Preparation method of 3-methyl-1-phenyl-1H-1,2, 4-triazole-5 (4H) -ketone | 湖南海利常德农药化工有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-115819358-B | Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt | 湖南化工研究院有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-114044758-B | Synthetic method of intermediate for preparing triazolinone herbicide sulfenamide | 浙大宁波理工学院 | 2024-03-26 | — | — | CN | disclosed |
| CN-115819358-A | Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt | 湖南化工研究院有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-112225705-B | Preparation method of 3-methyl-1-phenyl-1H-1,2, 4-triazole-5 (4H) -ketone | 湖南海利常德农药化工有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109232450-B | Synthetic method of sulfentrazone | 山东润博生物科技有限公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-112225705-A | Preparation method of 3-methyl-1-phenyl-1H-1,2, 4-triazole-5 (4H) -ketone | 湖南海利常德农药化工有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-111689915-A | Preparation method of 1- (2, 4-dichlorophenyl) -4-difluoromethyl-3-methyl-1H-1, 2, 4-triazole-5-ketone | 湖南斯派克科技股份有限公司 | 2020-09-22 | — | — | CN | disclosed |
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |