Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | LOX | P28300 | 1/20 | 0.48 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656287 | 0.81 | TP53 (0.49) | GAAMAPTCXCR2LOXLOXL2 | |
| SCHEMBL7659636 | 0.77 | MEN1 (0.51) | GAAMAPTCXCR2MEN1KMT2A | |
| SCHEMBL7650665 | 0.75 | KDM4E (0.64) | GAAMAPTLOXLOXL2MEN1 | |
| SCHEMBL7653827 | 0.74 | KDM4E (0.48) | GAAMAPTCXCR2MEN1KMT2A | |
| SCHEMBL7657337 | 0.74 | MGLL (0.46) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7656036 | 0.72 | ALKBH5 (0.50) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7652511 | 0.72 | KDM4E (0.51) | GAAMAPTLOXLOXL2MEN1 | |
| SCHEMBL7652914 | 0.71 | LMNA (0.46) | GAAMAPTLOXLOXL3LOXL2 | |
| SCHEMBL7656234 | 0.70 | ALDH1A1 (0.53) | GAAMAPTCXCR2LOXLOXL2 | |
| SCHEMBL7658239 | 0.70 | ALDH1A1 (0.62) | GAAMAPTLOXLOXL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |