Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 9/20 | 0.46 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652101 | 0.84 | KMT2A (0.55) | ALDH1A1KDM4ENPC1RAB9AP4HTM | |
| SCHEMBL7107999 | 0.82 | CNR2 (0.44) | KDM4EGLAL3MBTL1KMT2ACNR2 | |
| SCHEMBL11253022 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4ENPC1RAB9AGLA | |
| SCHEMBL8824679 | 0.74 | THRB (0.54) | ALDH1A1KDM4ENPC1RAB9AP4HTM | |
| SCHEMBL1020382 | 0.73 | P4HTM (0.59) | ALDH1A1KDM4ENPC1RAB9AP4HTM | |
| SCHEMBL7105213 | 0.73 | CNR2 (0.39) | KDM4EGLAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL9180143 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPC1RAB9AP4HTM | |
| SCHEMBL7660982 | 0.72 | POLB (0.56) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL19283447 | 0.72 | KDM4E (0.54) | ALDH1A1KDM4ENPC1RAB9AGLA | |
| SCHEMBL7108736 | 0.72 | CNR2 (0.38) | KDM4EGLAL3MBTL1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| WO-2020184628-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | 日産化学株式会社 | 2020-09-17 | — | — | WO | disclosed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |