Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LONP1 | P36776 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108736 | 0.93 | CNR2 (0.38) | CNR2KDM4EGLAL3MBTL1PDE5A | |
| SCHEMBL7107999 | 0.89 | CNR2 (0.44) | CNR2KDM4EGLAL3MBTL1PDE5A | |
| SCHEMBL7103718 | 0.76 | CNR1 (0.52) | KDM4ESMN1; SMN2CNR1 | |
| SCHEMBL7103507 | 0.76 | KMT2A (0.53) | CNR2KDM4ECNR1 | |
| SCHEMBL7658923 | 0.75 | CNR2 (0.53) | CNR2KDM4EL3MBTL1PDE5APOLB | |
| SCHEMBL7106764 | 0.73 | CNR1 (0.46) | CNR2CNR1 | |
| SCHEMBL7656358 | 0.73 | ALDH1A1 (0.49) | CNR2KDM4EGLAL3MBTL1POLB | |
| SCHEMBL7103670 | 0.72 | KMT2A (0.55) | CNR2KDM4ECNR1 | |
| SCHEMBL7660743 | 0.72 | KDM4E (0.47) | KDM4EGLAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL7109193 | 0.70 | ICAM1 (0.40) | CNR2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001944-B1 | PYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-10-01 | — | — | EP | claimed |