Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | TP53 | P04637 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | CDK2 | P24941 | 6/20 | 0.62 |
| ▸ | RECQL | P46063 | 6/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657770 | 0.89 | MEN1 (0.68) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL10037939 | 0.83 | MEN1 (0.76) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL7657981 | 0.82 | MAPT (0.64) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL7659883 | 0.80 | MAPT (0.71) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL12378689 | 0.80 | MEN1 (0.75) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL7652737 | 0.80 | MEN1 (0.68) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL25209431 | 0.79 | MAPT (0.57) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL10067898 | 0.78 | ADORA3 (0.71) | MEN1KMT2ATP53MAPTKDM4E | |
| SCHEMBL14259664 | 0.77 | TUBB4A (0.70) | MEN1KMT2ATP53MAPTKDM4E | |
| Fisetin SCHEMBL116861 | 0.77 | MEN1 (1.00) | MEN1KMT2ATP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | claimed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | claimed |
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |