Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230540 | 0.80 | KMT2A (0.48) | KMT2AMAPK1AOC3 | |
| SCHEMBL29061992 | 0.78 | KMT2A (0.49) | KMT2AAOC3 | |
| SCHEMBL7652207 | 0.78 | KMT2A (0.49) | KMT2AAOC3 | |
| SCHEMBL31347526 | 0.77 | ALDH1A1 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL9230531 | 0.77 | KMT2A (0.51) | KMT2AMAPK1AOC3PDE4A | |
| SCHEMBL7404547 | 0.77 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3POLBALDH1A1 | |
| SCHEMBL7657764 | 0.76 | SLC6A3 (0.52) | SLC6A2SLC6A4SLC6A3POLBKMT2A | |
| SCHEMBL7371959 | 0.76 | KMT2A (0.47) | SLC6A2SLC6A4SLC6A3KMT2AAOC3 | |
| SCHEMBL7410294 | 0.76 | KMT2A (0.47) | KMT2AAOC3 | |
| SCHEMBL2647149 | 0.75 | POLB (0.52) | SLC6A2SLC6A4SLC6A3POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |