Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246228 | 0.81 | CHRM2 (0.60) | SLC6A3ALDH1A1SLC6A2SLC6A4CHRM2 | |
| SCHEMBL7840990 | 0.80 | SLC6A3 (0.56) | SLC6A3ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4243548 | 0.77 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL26144985 | 0.77 | ALDH1A1 (0.47) | SLC6A3ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7410719 | 0.77 | SLC6A2 (0.53) | SLC6A3ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7656632 | 0.76 | SLC6A2 (0.44) | SLC6A3ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7236494 | 0.76 | SLC6A3 (0.57) | SLC6A3MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL961019 | 0.76 | SLC6A3 (0.57) | SLC6A3MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL959762 | 0.74 | SLC6A3 (0.58) | SLC6A3MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL13124077 | 0.74 | SLC6A3 (0.58) | SLC6A3MEN1KMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358973-B1 | FOR THERAPY OF ALLERGIC OR INFLAMMATORY DISEASE | ZAMBON GROUP S.P.A. (IT) | 2002-03-19 | — | — | US | disclosed |