Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | PTGES | O14684 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7551596 | 0.88 | PPARG (0.46) | MMP9MMP13ADAM17EPHX1EPHX2 | |
| SCHEMBL6931969 | 0.85 | MMP9 (0.55) | MMP9MMP13ADAM17EPHX1EPHX2 | |
| SCHEMBL7650530 | 0.80 | MMP9 (0.46) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL7656991 | 0.78 | PPARG (0.56) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL7465093 | 0.77 | PPARG (0.51) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL7554706 | 0.76 | SMN1; SMN2 (0.46) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL8856146 | 0.71 | PPARG (0.52) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL10377002 | 0.70 | MMP9 (0.45) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL6656240 | 0.70 | ALOX5 (0.49) | MMP9MMP13ADAM17PPARGALOX5 | |
| SCHEMBL7070103 | 0.69 | ALOX5 (0.53) | EPHX2PPARGALOX5PPARAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462073-B2 | METALLOPROTEASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION | 2002-10-08 | — | — | US | disclosed |
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |